: An underdeveloped intestinal immune system that struggles to clear common bacterial infections, such as Citrobacter rodentium . 2. Cancer Research and Therapeutics
Research published in PNAS suggests that expressing RARα (alongside other factors) can drastically speed up and improve the efficiency of reprogramming somatic cells into pluripotent stem cells. Summary of Key Research Tools 21703.rar
RARα is essential for maintaining the balance of the gut. A lack of RARα signaling in intestinal cells can lead to: : An underdeveloped intestinal immune system that struggles
: An overproduction of goblet and Paneth cells, which can disrupt normal gut function. which can disrupt normal gut function.