: Showing the progression of a cell through mitosis.

: Without proper Chmp4c function, cells often experience errors in chromosome alignment, leading to genomic instability.

The study investigates the role of , a protein traditionally known for its function in the ESCRT-III (Endosomal Sorting Complex Required for Transport) pathway, which typically handles late-stage cell division (abscission). The researchers discovered that Chmp4c has a much earlier role:

: The paper demonstrates that Chmp4c is required for the proper timing of mitosis; its absence can cause a significant delay in the cell cycle. Significance of the .mp4 File

In scientific publishing, identifiers like "39091" are often used by the journal's hosting platform (in this case, Rockefeller University Press) to link specific multimedia files to their corresponding articles. The video labeled typically displays time-lapse microscopy of:

: Visualizing how the spindle forms and interacts with chromosomes in both control cells and Chmp4c-depleted cells to illustrate the paper's findings.

: It helps regulate the organization and stability of the mitotic spindle , the machinery that pulls chromosomes apart during cell division.