Elevated AFP levels may indicate neural tube defects (such as spina bifida or anencephaly), abdominal wall defects, twin pregnancy, or an incorrectly estimated gestational age.
1. Alpha-Fetoprotein (AFP) in Pregnancy (Prenatal Screening)
Lower than normal levels may indicate Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18).
The maternal serum AFP (MSAFP) test is a blood test performed during the second trimester (typically between 15 and 20 weeks) to assess the risk of fetal abnormalities.