Determining the expected variability of immune cell populations is a foundational step in defining a "healthy" immune baseline and identifying clinically relevant anomalies. Research indicates that while an individual's immune profile is remarkably stable over time, there is massive —often spanning several orders of magnitude—among healthy people. Core Drivers of Immune Variability
Most immune variation is driven by life experiences and environmental exposures. Determining the expected variability of immune ...
B cell subsets and certain antibodies like IgG1 show significant fluctuations based on the time of year. Determining the expected variability of immune ...
The most potent intrinsic driver, causing a shift from precursor-biased (naïve) status to an inflammation-biased status. Determining the expected variability of immune ...