Other users like Sonfaro and Cpt Charisma also provided converted story packs for the same community. Scientific Context (ERK and RAR)
A signaling pathway that generally regulates cell growth and proliferation. Download ERK rar
A nuclear receptor that mediates the effects of Vitamin A (retinoic acid) to control cell differentiation. Other users like Sonfaro and Cpt Charisma also
Studies have shown that ERK signaling can suppress RAR activity in breast cancer cells, leading to "retinoid resistance". Conversely, using MEK inhibitors (which block ERK) can enhance the tumor-suppressive effects of retinoic acid. leading to "retinoid resistance". Conversely