Get the latest version of DeSmuME from the official site . Extract: Use a tool like 7-Zip to unzip the emulator files.
Open DeSmuME.exe , go to File > Open ROM , and select your ds-hikeisle.iso file. 2. Play on Nintendo DS/3DS (Hardware) ds-hikeisle.iso
To play the ISO on your computer, you will need a Nintendo DS emulator like DeSmuME . Get the latest version of DeSmuME from the official site
To run the ISO on original hardware, you must use a flashcard (like an R4 card) or a modded console. Hike Isle Gameplay | Nintendo Switch go to File > Open ROM