Dr. Mesecar's team played a crucial role in identifying the antiviral X77 , which was effective against the SARS-CoV-2 main protease ( Mprocap M raised to the p r o power
He specializes in determining high-resolution 3D structures of enzymes (such as 3CLpro and PLpro) in coronaviruses and cancer to design selective drugs. mesecar
He is involved in translational research to turn basic molecular findings into commercial drugs for cancer and Alzheimer's disease. ), helping guide the development of treatments like
), helping guide the development of treatments like . mesecar
His work includes developing non-covalent, selective inhibitors designed to work against multiple emerging coronavirus strains, including MERS-CoV.
He is the Robert Wallace Miller Director of the Purdue Institute for Cancer Research , where he leads efforts in developing novel cancer therapies, diagnostics, and targeting cancer at the cellular level.
Dr. Andrew Mesecar is a prominent researcher specializing in biochemistry, structural biology, and cancer drug discovery. His key research features and contributions include: