Prilosec File

: While its plasma half-life is short (less than 1 hour), its inhibitory effect on acid secretion lasts much longer because the binding to the proton pump is covalent. Full therapeutic effects often take 1 to 4 days to develop. 5. Safety and Adverse Effects

: Primarily metabolized in the liver by the cytochrome P450 enzyme system, specifically CYP2C19 . prilosec

: Potential malabsorption of vitamin B12, magnesium, and calcium. : While its plasma half-life is short (less

: Some studies link long-term PPI use to an increased risk of bone fractures. prilosec